000 | 03022cam a2200445 i 4500 | ||
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001 | 17904169 | ||
003 | KPN | ||
005 | 20211006155806.0 | ||
008 | 130930s2014 nyua b 001 0 eng | ||
010 | _a 2013039646 | ||
020 | _a9781451655667 (hardback) | ||
020 | _a9781451655674 (trade paperback) | ||
020 | _z9781451655698 (ebook) | ||
040 |
_aDNLM/DLC _cDLC _erda _dDLC |
||
042 | _apcc | ||
050 | 0 | 0 |
_aRA401.A3 _bW37 2014 |
060 | 1 | 0 | _aQV 736 AA1 |
082 | 0 | 0 |
_a338.4/76151 _223 |
100 | 1 |
_aWerth, Barry, _eauthor. |
|
245 | 1 | 4 |
_aThe antidote : _binside the world of new pharma / _cBarry Werth. |
250 | _aFirst Simon & Schuster hardcover edition. | ||
260 |
_aNew York _bSimon & Schuster _c2014 |
||
264 | 1 |
_aNew York : _bSimon & Schuster, _c2014. |
|
300 |
_ax, 435 pages : _billustration ; _c25 cm |
||
336 |
_atext _2rdacontent |
||
337 |
_aunmediated _2rdamedia |
||
338 |
_avolume _2rdacarrier |
||
504 | _aIncludes bibliographic references (pages 401-416) and index. | ||
520 | _a"This is the Moneyball of the pharma world, the story of one drug company's quest to transform the pharmaceutical industry and a deeply revealing look into a world where breakneck capitalism meets life-saving medicine.The $325 billion-a-year pharmaceutical business is America's most challenging and one of its most profitable. It is tougher in just about every way than any other enterprise: from the towering biological risks inherent in its mission to treat disease; to the thirty-to-one failure rate in bringing out a successful medicine after a candidate clears all the hurdles to get to human testing; to the billion-dollar-plus cost of ramping up a successful product; to operating in the worlds most highly regulated industry with the possible exception of nuclear power. The Antidote tells the story of Vertex, a maverick drug company led by the charismatic Joshua Boger and a small group of entrepreneurial young scientists who broke off from Merck when it was the world's best drug maker, indeed the most admired business in America because they thought they could make drugs better. Building upon his widely praised The Billion-Dollar Molecule, Barry Werth captures the full scope of Vertex's twenty-five-year drive to liver breakthrough medicines and transform the drug industry. The Antidote draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking close-up of Vertex's inner workings and the ferocious but indispensable world it inhabits"--Provided by publisher. | ||
546 | _aIn English | ||
610 | 2 | 2 | _aVertex Pharmaceuticals Incorporated. |
650 | 1 | 2 |
_aDrug Industry _zUnited States. |
650 | 2 | 2 |
_aDrug Industry _xhistory _zUnited States. |
650 | 2 | 2 |
_aHistory, 20th Century _zUnited States. |
650 | 2 | 2 |
_aHistory, 21st Century _zUnited States. |
650 | 2 | 2 |
_aTechnology, Pharmaceutical _zUnited States. |
906 |
_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg |
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942 |
_2ddc _c1 _n0 |
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999 |
_c237 _d237 |