000 03022cam a2200445 i 4500
001 17904169
003 KPN
005 20211006155806.0
008 130930s2014 nyua b 001 0 eng
010 _a 2013039646
020 _a9781451655667 (hardback)
020 _a9781451655674 (trade paperback)
020 _z9781451655698 (ebook)
040 _aDNLM/DLC
_cDLC
_erda
_dDLC
042 _apcc
050 0 0 _aRA401.A3
_bW37 2014
060 1 0 _aQV 736 AA1
082 0 0 _a338.4/76151
_223
100 1 _aWerth, Barry,
_eauthor.
245 1 4 _aThe antidote :
_binside the world of new pharma /
_cBarry Werth.
250 _aFirst Simon & Schuster hardcover edition.
260 _aNew York
_bSimon & Schuster
_c2014
264 1 _aNew York :
_bSimon & Schuster,
_c2014.
300 _ax, 435 pages :
_billustration ;
_c25 cm
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes bibliographic references (pages 401-416) and index.
520 _a"This is the Moneyball of the pharma world, the story of one drug company's quest to transform the pharmaceutical industry and a deeply revealing look into a world where breakneck capitalism meets life-saving medicine.The $325 billion-a-year pharmaceutical business is America's most challenging and one of its most profitable. It is tougher in just about every way than any other enterprise: from the towering biological risks inherent in its mission to treat disease; to the thirty-to-one failure rate in bringing out a successful medicine after a candidate clears all the hurdles to get to human testing; to the billion-dollar-plus cost of ramping up a successful product; to operating in the worlds most highly regulated industry with the possible exception of nuclear power. The Antidote tells the story of Vertex, a maverick drug company led by the charismatic Joshua Boger and a small group of entrepreneurial young scientists who broke off from Merck when it was the world's best drug maker, indeed the most admired business in America because they thought they could make drugs better. Building upon his widely praised The Billion-Dollar Molecule, Barry Werth captures the full scope of Vertex's twenty-five-year drive to liver breakthrough medicines and transform the drug industry. The Antidote draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking close-up of Vertex's inner workings and the ferocious but indispensable world it inhabits"--Provided by publisher.
546 _aIn English
610 2 2 _aVertex Pharmaceuticals Incorporated.
650 1 2 _aDrug Industry
_zUnited States.
650 2 2 _aDrug Industry
_xhistory
_zUnited States.
650 2 2 _aHistory, 20th Century
_zUnited States.
650 2 2 _aHistory, 21st Century
_zUnited States.
650 2 2 _aTechnology, Pharmaceutical
_zUnited States.
906 _a7
_bcbc
_corignew
_d1
_eecip
_f20
_gy-gencatlg
942 _2ddc
_c1
_n0
999 _c237
_d237