Werth, Barry,

The antidote : inside the world of new pharma / Barry Werth. - First Simon & Schuster hardcover edition. - New York Simon & Schuster 2014 - x, 435 pages : illustration ; 25 cm

Includes bibliographic references (pages 401-416) and index.

"This is the Moneyball of the pharma world, the story of one drug company's quest to transform the pharmaceutical industry and a deeply revealing look into a world where breakneck capitalism meets life-saving medicine.The $325 billion-a-year pharmaceutical business is America's most challenging and one of its most profitable. It is tougher in just about every way than any other enterprise: from the towering biological risks inherent in its mission to treat disease; to the thirty-to-one failure rate in bringing out a successful medicine after a candidate clears all the hurdles to get to human testing; to the billion-dollar-plus cost of ramping up a successful product; to operating in the worlds most highly regulated industry with the possible exception of nuclear power. The Antidote tells the story of Vertex, a maverick drug company led by the charismatic Joshua Boger and a small group of entrepreneurial young scientists who broke off from Merck when it was the world's best drug maker, indeed the most admired business in America because they thought they could make drugs better. Building upon his widely praised The Billion-Dollar Molecule, Barry Werth captures the full scope of Vertex's twenty-five-year drive to liver breakthrough medicines and transform the drug industry. The Antidote draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking close-up of Vertex's inner workings and the ferocious but indispensable world it inhabits"--Provided by publisher.

In English

9781451655667 (hardback) 9781451655674 (trade paperback)


Vertex Pharmaceuticals Incorporated.

Drug Industry--United States.
Drug Industry--history--United States.
History, 20th Century--United States.
History, 21st Century--United States.
Technology, Pharmaceutical--United States.

RA401.A3 / W37 2014


QV 736 AA1